Memories of kuru while at Okapa, Papua New Guinea in 1957
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Memories of kuru while at Okapa, Papua New Guinea in 1957
Before going to Okapa, I had worked in Papua New Guinea (PNG) for 6 years and done nutrition surveys in various parts of the country. The Okapa survey was different because this time I was searching for something unusual in food that could have caused the fatal disease ‘kuru’, so called by the local Fore people owing to the ‘shaking’ that characterizes it. Conducting this study meant that I had...
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Kuru is so far the principal human epidemic prion disease. While its incidence has steadily declined since the cessation of its route of transmission, endocannibalism, in Papua New Guinea in the 1950s, the arrival of variant Creutzfeldt-Jakob disease (vCJD), also thought to be transmitted by dietary prion exposure, has given kuru a new global relevance. We investigated all suspected cases of ku...
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I first heard of ‘de lachende ziekte’ on Dutch newsprint and radio in 1957 while at high school, then promptly forgot about it until my medical school years. My impression of the first patient I saw demonstrated in clinical neurology class was vague. The first visit to Okapa (1964–1965) was bland. The class of eight arrived at 7 in the evening and left for ‘kuru ward round’ at 6 the next mornin...
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ژورنال
عنوان ژورنال: Philosophical Transactions of the Royal Society B: Biological Sciences
سال: 2008
ISSN: 0962-8436,1471-2970
DOI: 10.1098/rstb.2008.4026